Publications

Peer-reviewed articles, conference papers, preprints, and book chapters.

L-MAE: Longitudinal Masked Auto-Encoder for Diabetic Retinopathy Progression Prediction

Rachid Youven Zeghlache, Pierre-Henri Conze, Gwenolé Quellec, Mathieu Lamard, Béatrice Cochener, Gouenou Coatrieux

Computers in Biology and Medicine (CBM), 2025

We propose L-MAE, a longitudinal masked auto-encoder that learns temporal representations from sequential retinal image pairs to predict diabetic retinopathy progression.
longitudinalmasked-autoencoderdiabetic-retinopathydeep-learning
DISCOVER: Development and Validation of a Deep Learning-Based Algorithm for Diabetic Retinopathy Progression Prediction

Rachid Youven Zeghlache, Pierre-Henri Conze, Gwenolé Quellec, Mathieu Lamard, Sophie Bonnin, Béatrice Cochener, Gouenou Coatrieux

AIM — Artificial Intelligence in Medicine, 2024

Development and external validation of a deep learning algorithm for predicting diabetic retinopathy progression from baseline fundus photographs.
diabetic-retinopathyprogression-predictiondeep-learningvalidation
Deep Learning for Diabetic Retinopathy Screening — A Comprehensive Review

Rachid Youven Zeghlache, Pierre-Henri Conze, Gwenolé Quellec, Mathieu Lamard, Béatrice Cochener, Gouenou Coatrieux

Computers in Biology and Medicine (CBM), 2024

A comprehensive review of deep learning methods applied to diabetic retinopathy screening, covering datasets, architectures, and evaluation protocols.
reviewdiabetic-retinopathydeep-learningscreening
Multi-modal Deep Learning for Age-related Macular Degeneration Progression Prediction

Rachid Youven Zeghlache, Pierre-Henri Conze, Gwenolé Quellec, Mathieu Lamard, Béatrice Cochener, Gouenou Coatrieux

arXiv preprint, 2025

A multi-modal deep learning framework combining OCT and fundus imaging for AMD progression prediction, evaluated on the MARIO MICCAI 2024 challenge dataset.
amdmulti-modaloctprogression-prediction
LatiM: Longitudinal Representation Learning in Continuous-Time Models for Medical Image Analysis

Rachid Youven Zeghlache, Pierre-Henri Conze, Gwenolé Quellec, Mathieu Lamard, Béatrice Cochener, Gouenou Coatrieux

MICCAI 2024, 2024

LatiM is a continuous-time longitudinal model for learning representations from sequential medical images, enabling disease progression prediction from irregular time-series.
longitudinalcontinuous-timemiccaimedical-imaging
Longitudinal Self-Supervised Learning using Neural Ordinary Differential Equation

Rachid Youven Zeghlache, Pierre-Henri Conze, Gwenolé Quellec, Mathieu Lamard, Béatrice Cochener, Gouenou Coatrieux

PRIME Workshop, MICCAI 2023, 2023

Self-supervised longitudinal learning via Neural ODEs for retinal image sequences applied to diabetic retinopathy follow-up and progression prediction.
self-supervisedneural-odelongitudinalmiccai
LMT: Longitudinal Mixing Training for Disease Progression Prediction using Multi-Source Data

Rachid Youven Zeghlache, Pierre-Henri Conze, Gwenolé Quellec, Mathieu Lamard, Béatrice Cochener, Gouenou Coatrieux

MLMI Workshop, MICCAI 2023, 2023

LMT enables predicting disease progression from a single image at inference time by leveraging longitudinal data mixing during training.
longitudinaldata-augmentationprogressionmiccai
Detection of Diabetic Retinopathy using Longitudinal Self-Supervised Learning

Rachid Youven Zeghlache, Pierre-Henri Conze, Gwenolé Quellec, Mathieu Lamard, Béatrice Cochener, Gouenou Coatrieux

OMIA Workshop, MICCAI 2022 — 🏆 Best Paper, 2022

Best Paper Award. Longitudinal self-supervised learning applied to retinal fundus image sequences for automated diabetic retinopathy detection.
best-paperdiabetic-retinopathyself-supervisedomiamiccai
Method and System for Longitudinal Medical Image Analysis using Deep Learning

Rachid Youven Zeghlache, Pierre-Henri Conze, Gwenolé Quellec, Mathieu Lamard, Béatrice Cochener, Gouenou Coatrieux

European Patent Office — EP23306730.5, 2023

Patent covering a deep learning method for longitudinal analysis of medical images, enabling progression monitoring and prediction for degenerative diseases.
patentlongitudinalmedical-imagingdeep-learning
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